The term Claudin-low explained
Once you get the results back from the several (thousand) tests you have had done prior to your breast cancer diagnosis you are often left spinning in acronyms and new words.
The first term you often come across is Triple Negative. This is a standard term used for all cancers that are home negative.
When you dig deeper you get to find out about the molecular subtype. There are four main types of molecular subtypes. I am not an expert on all of them they are:
It is not a main type but the other type of molecular subtype of cancer is called Claudin Low. This is what I have and this is how Metaplastic Breast Cancer is categorised. http://breast-cancer-research.com/content/12/5/r68
Very very simply – Claudin Low cancers said to be more like stem-cells. The have a low number of proteins. These proteins are called claudins. Claudin Low is a rarer molecular subtype signifies a higer grade cancer. Metaplastic breast cancer is a Claudin Low subtype.
So you have Caludin Low on your pathology report… now what?
You need to be aggressive with your cancer. Fight back with chemotherapy. The success rate for metaplastic breast cancer, if you survive the first year is excellent.